⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12817498 | 0.87 | — | — | |
| SCHEMBL30807 | 0.82 | — | — | |
| SCHEMBL64228 | 0.76 | — | — | |
| SCHEMBL9820356 | 0.74 | — | — | |
| Water SCHEMBL11399021 | 0.71 | — | — | |
| SCHEMBL256063 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL901105 | 0.71 | — | — | |
| SCHEMBL14022374 | 0.70 | — | — | |
| SCHEMBL1998298 | 0.65 | — | — | |
| SCHEMBL1203 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134466-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS, SUBSTITUTED HETEROARYLAMINE COMPOUNDS, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-06-27 | — | — | WO | claimed |
| WO-2023240024-A1 | SULFAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023192801-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | claimed |
| US-20230303509-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. | 2023-09-28 | — | — | US | claimed |
| EP-4168409-A1 | VMAT2 INHIBITORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | claimed |
| CN-109153665-B | Novel 2-substituted indazoles, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2021-10-15 | — | — | CN | claimed |
| CN-112920199-A | Piperazinone substituent or derivative thereof, and preparation method, application and pharmaceutical composition thereof | 四川大学 | 2021-06-08 | — | — | CN | claimed |
| EP-3321262-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2021-01-13 | — | — | EP | claimed |
| EP-3590933-B1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | GENENTECH INC (US) | 2021-01-06 | — | — | EP | claimed |
| US-4906286-A | Herbicidal 2-aryl-1,2,4-triazine-3,5(2H,4H)-diones and sulfur analogs thereof | FMC CORPORATION (US) | 1990-03-06 | — | — | US | claimed |
| US-4895940-A | Process for the preparation of penems | PFIZER INC. (US) | 1990-01-23 | — | — | US | claimed |
| EP-0185731-A4 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1988-11-02 | — | — | EP | claimed |
| EP-0130025-B1 | 2-ALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1987-07-08 | — | — | EP | claimed |
| US-4619924-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | claimed |
| EP-0185731-A1 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF | FMC Corporation (US) | 1986-07-02 | — | — | EP | claimed |
| WO-1986000072-A1 | HERBICIDAL 2-ARYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1986-01-03 | — | — | WO | claimed |
| EP-0157876-A1 | HERBICIDAL 1-ARYL-$g(D)?2 -1,2,4-TRIAZOLIN-5-ONES | FMC Corporation (US) | 1985-10-16 | — | — | EP | claimed |
| WO-1985001637-A1 | HERBICIDAL 1-ARYL-DELTA2-1,2,4-TRIAZOLIN-5-ONES | FMC CORPORATION (US) | 1985-04-25 | — | — | WO | claimed |
| EP-0130025-A1 | 2-Alkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-02 | — | — | EP | claimed |