Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740501 | 0.93 | CYP3A4 (0.48) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E | |
| SCHEMBL13520593 | 0.83 | ALDH1A1 (0.64) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E | |
| SCHEMBL28352745 | 0.82 | CA1 (0.46) | CYP2C9CYP2C19CYP1A2TDP1ALDH1A1 | |
| SCHEMBL23266142 | 0.81 | ALDH1A1 (0.47) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E | |
| SCHEMBL7833889 | 0.79 | CYP3A4 (0.67) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E | |
| SCHEMBL31026506 | 0.79 | CYP3A4 (0.67) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E | |
| SCHEMBL7705813 | 0.77 | FFAR1 (0.55) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E | |
| SCHEMBL30022461 | 0.77 | CA1 (0.60) | CYP3A4KDM4EMAPTTDP1LMNA | |
| SCHEMBL4214499 | 0.77 | CA1 (0.60) | CYP3A4KDM4EMAPTTDP1LMNA | |
| SCHEMBL6814216 | 0.77 | FFAR1 (0.47) | CYP2C9CYP2C19CYP3A4CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024261504-A1 | BENZOFURAN-3-CARBOXYLIC ACID AMIDES AND BENZOFURAN-3- CARBONYL-BENZAMIDES, METHOD FOR THEIR PRODUCTION WITH HIGH SELECTIVITY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PÉCSI TUDOMÁNYEGYETEM (HU) | 2024-12-26 | — | — | WO | disclosed |