SCHEMBL3131471

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3121109	0.89	SCN9A (0.45)	SCN9AIKBKBCYP3A4KMT2AMEN1
	SCHEMBL13414012	0.89	RAB9A (0.49)	SCN9AIKBKBKMT2AMEN1TP53
	SCHEMBL13414023	0.89	SCN9A (0.44)	SCN9AIKBKBCYP3A4KMT2AMEN1
	SCHEMBL3119522	0.87	ROCK1 (0.45)	SCN9AIKBKBCYP3A4AGPAT2KCNH2
	SCHEMBL3140666	0.87	SCN9A (0.50)	SCN9AIKBKBCYP3A4KMT2AMEN1
	SCHEMBL13414016	0.87	AGPAT2 (0.42)	SCN9AIKBKBCYP3A4KMT2AMEN1
	SCHEMBL3117362	0.87	AGPAT2 (0.56)	SCN9AIKBKBAGPAT2KCNH2SCN5A
	SCHEMBL1644554	0.87	AGPAT2 (0.55)	SCN9AIKBKBKMT2AMEN1TP53
	SCHEMBL3146439	0.87	ROCK1 (0.47)	SCN9AIKBKBCYP3A4KMT2AMEN1
	SCHEMBL3117404	0.86	SCN9A (0.41)	SCN9AIKBKBCYP3A4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.