SCHEMBL31315537

SCHEMBL31315537

CCn1cc(-c2cc(Cn3ccn(C)/c3=N\C(=O)OC(C)(C)C)cc3c2OCC(Cc2ccc(F)c(O)c2)C3=O)c(C(F)(F)F)n1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 9/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30427226 0.93 WDR5 (0.36) WDR5
SCHEMBL25191850 0.93 WDR5 (0.36) WDR5
SCHEMBL25186889 0.93 WDR5 (0.36) WDR5
SCHEMBL30427498 0.92 WDR5 (0.36) WDR5
SCHEMBL30427293 0.91 WDR5 (0.36) WDR5
SCHEMBL25187070 0.91 WDR5 (0.36) WDR5
SCHEMBL25187074 0.91 WDR5 (0.36) WDR5
SCHEMBL31315560 0.91 WDR5 (0.36) WDR5
SCHEMBL31315498 0.90 WDR5 (0.36) WDR5
SCHEMBL30427301 0.90 WDR5 (0.36) WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024232597-A1 4-CHROMANONE COMPOUNDS THAT DEGRADE WDR5 AND USES THEREOF 엘젠테라퓨틱스 주식회사 2024-11-14 WO disclosed