Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 15/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25188022 | 1.00 | WDR5 (0.59) | WDR5PDE3BPDE3AKCNH2EED | |
| SCHEMBL25187166 | 0.89 | WDR5 (0.54) | WDR5 | |
| SCHEMBL22750309 | 0.88 | WDR5 (0.57) | WDR5PDE3BPDE3AKCNH2 | |
| SCHEMBL29767270 | 0.88 | WDR5 (0.57) | WDR5PDE3BPDE3AKCNH2 | |
| SCHEMBL22766405 | 0.81 | WDR5 (0.78) | WDR5KCNH2 | |
| SCHEMBL29767249 | 0.81 | WDR5 (0.78) | WDR5KCNH2 | |
| SCHEMBL22750297 | 0.80 | WDR5 (0.64) | WDR5KCNH2 | |
| SCHEMBL29767087 | 0.80 | WDR5 (0.64) | WDR5KCNH2 | |
| SCHEMBL24885723 | 0.79 | WDR5 (0.68) | WDR5 | |
| SCHEMBL24886267 | 0.79 | WDR5 (0.66) | WDR5PDE3BPDE3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024232597-A1 | 4-CHROMANONE COMPOUNDS THAT DEGRADE WDR5 AND USES THEREOF | 엘젠테라퓨틱스 주식회사 | 2024-11-14 | — | — | WO | disclosed |