Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.37 |
| ▸ | TUBB | P07437 | 4/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26683598 | 0.88 | TFPI2 (0.46) | S100BALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL12068038 | 0.87 | TFPI2 (0.53) | NOTUMALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL25337670 | 0.82 | PIK3CD (0.43) | S100BALDH1A1KDM4ETFPI2TUBB1 | |
| SCHEMBL20977900 | 0.82 | NOTUM (0.46) | NOTUMALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL29833060 | 0.80 | TFPI2 (0.38) | S100BALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL14115781 | 0.79 | NOTUM (0.44) | NOTUMALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL31316159 | 0.78 | TDP1 (0.47) | NOTUMALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL31316141 | 0.73 | TUBB1 (0.62) | NOTUMALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL28550833 | 0.73 | TUBB1 (0.62) | NOTUMALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL28409121 | 0.73 | MTNR1A (0.55) | NOTUMALDH1A1KDM4EHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241548-A | Dihydropteridinone derivatives containing fused benzene rings and use thereof | 沈阳药科大学 | 2025-01-03 | — | — | CN | disclosed |