Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30063672 | 1.00 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL29171542 | 1.00 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL24913143 | 1.00 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL24913153 | 1.00 | PIK3CA (0.40) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL26662510 | 0.90 | ALDH1A1 (0.37) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL30584325 | 0.90 | ALDH1A1 (0.37) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL26662521 | 0.90 | ALDH1A1 (0.37) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL31481660 | 0.88 | CSNK2A2 (0.43) | PIK3CAAKT1AKT2AKT3ALDH1A1 | |
| SCHEMBL26880839 | 0.81 | PIK3CA (0.41) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 | |
| SCHEMBL31316385 | 0.79 | ALDH1A1 (0.47) | PIK3CAPIK3CBPIK3CDPIK3CGAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301106-A | Allosteric benzopyrone inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2025-01-10 | — | — | CN | disclosed |