Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19578925 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL25495773 | 0.87 | ALDH1A1 (0.31) | ALDH1A1CYP1A2CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL25495772 | 0.87 | ALDH1A1 (0.31) | ALDH1A1CYP1A2CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL16564870 | 0.87 | ALDH1A1 (0.31) | ALDH1A1CYP1A2CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL16564884 | 0.87 | ALDH1A1 (0.31) | ALDH1A1CYP1A2CYP3A4CYP2D6HSD17B10 | |
| SCHEMBL25264994 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL30360115 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL25189956 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL25264993 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL31471427 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2ATML3MBTL1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |