Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564871 | 0.82 | DPP4 (0.39) | DPP4HTR2ACYP2C19PYCR1CYP2A6 | |
| SCHEMBL7435987 | 0.81 | CHRNA7 (0.40) | CYP2C19SLC6A4MAOAALDH1A1 | |
| SCHEMBL21009888 | 0.81 | ATM (0.46) | CYP2C19SLC6A4MAPK1 | |
| SCHEMBL4628662 | 0.81 | DPP4 (0.41) | DPP4CYP2C19SLC6A4 | |
| SCHEMBL30481074 | 0.81 | ATM (0.46) | CYP2C19SLC6A4MAPK1 | |
| SCHEMBL25187548 | 0.81 | DPP4 (0.41) | DPP4CYP2C19SLC6A4 | |
| SCHEMBL5428734 | 0.81 | DPP4 (0.41) | DPP4CYP2C19SLC6A4 | |
| SCHEMBL7406881 | 0.80 | CYP2C19 (0.57) | DPP4HTR2ACYP2C19ALDH1A1ALOX15 | |
| SCHEMBL898390 | 0.80 | CYP2C19 (0.57) | DPP4HTR2ACYP2C19ALDH1A1ALOX15 | |
| SCHEMBL4629946 | 0.80 | CYP2C19 (0.57) | DPP4HTR2ACYP2C19ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |