Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406881 | 1.00 | CYP2C19 (0.57) | CYP2C19SMN1; SMN2SCN4ADPP4F2 | |
| SCHEMBL898390 | 1.00 | CYP2C19 (0.57) | CYP2C19SMN1; SMN2SCN4ADPP4F2 | |
| Hydrochloric Acid SCHEMBL25188226 | 0.98 | CYP2C19 (0.55) | CYP2C19SMN1; SMN2SCN4ADPP4F2 | |
| Hydrochloric Acid SCHEMBL31471464 | 0.98 | CYP2C19 (0.55) | CYP2C19SMN1; SMN2SCN4ADPP4F2 | |
| Hydrochloric Acid SCHEMBL250191 | 0.98 | CYP2C19 (0.55) | CYP2C19SMN1; SMN2SCN4ADPP4F2 | |
| SCHEMBL28590509 | 0.83 | CYP2C19 (0.46) | CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL22705600 | 0.82 | SCN4A (0.45) | SCN4ADPP4F2GRIN2DGRIN3B | |
| SCHEMBL31316848 | 0.80 | DPP4 (0.42) | CYP2C19DPP4ALDH1A1ALOX15HTR2A | |
| SCHEMBL5445894 | 0.78 | DPP4 (0.43) | CYP2C19SMN1; SMN2DPP4ALDH1A1MAPT | |
| SCHEMBL21009888 | 0.78 | ATM (0.46) | CYP2C19SCN4AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118185450-A | Modified polyurethane primer and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116606592-B | UV (ultraviolet) light-cured waterborne polyurethane primer for vehicles and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-116606592-A | UV (ultraviolet) light-cured waterborne polyurethane primer for vehicles and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-114395378-B | Synthesis of high-temperature-resistant modified nano-alumina plugging agent and oil-based drilling fluid | 西南石油大学 | 2023-01-31 | — | — | CN | claimed |
| CN-114395378-A | Synthesis of high-temperature-resistant modified nano-alumina plugging agent and oil-based drilling fluid | 西南石油大学 | 2022-04-26 | — | — | CN | claimed |
| CN-118185450-A | Modified polyurethane primer and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116606592-B | UV (ultraviolet) light-cured waterborne polyurethane primer for vehicles and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116606592-A | UV (ultraviolet) light-cured waterborne polyurethane primer for vehicles and preparation method thereof | 广东普赛达密封粘胶有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-114395378-B | Synthesis of high-temperature-resistant modified nano-alumina plugging agent and oil-based drilling fluid | 西南石油大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-114395378-A | Synthesis of high-temperature-resistant modified nano-alumina plugging agent and oil-based drilling fluid | 西南石油大学 | 2022-04-26 | — | — | CN | disclosed |
| US-20170226105-A1 | TIED-BACK BENZAMIDE DERIVATIVES AS POTENT ROCK INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170226105-A1 | TIED-BACK BENZAMIDE DERIVATIVES AS POTENT ROCK INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-10 | — | — | US | disclosed |
| WO-2005063682-A1 | IMPROVED METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-07-14 | — | — | WO | disclosed |
| EP-0770077-B1 | PROCESS FOR THE PREPARATION OF 2-(1-AZABICYCLO(2.2.2)OCT-3-YL) -2,4,5,6-TETRAHYDRO-1H-BENZ(DE)ISOQUINOLIN-1-ONE AND INTERMEDIATE PRODUCT | HOFFMANN LA ROCHE (CH) | 2001-09-19 | — | — | EP | disclosed |
| EP-0770077-A1 | PROCESS FOR THE PREPARATION OF 2-(1-AZABICYCLO(2.2.2)OCT-3-YL) -2,4,5,6-TETRAHYDRO-1H-BENZ(DE)ISOQUINOLIN-1-ONE AND INTERMEDIATE PRODUCT | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-02 | — | — | EP | disclosed |
| US-5576434-A | (1-azabicyclo[2.2.2]oct-3-yl) (1,2,3,4-tetrahydronaphthalen-1-ylmethyl)amine and n-(1-azabicyclo[2.2.2]oc | HELSINN HEALTHCARE SA (CH) | 1996-11-19 | — | — | US | disclosed |
| US-5567818-A | Processes for preparing 2-(1-azabicyclo[2.2.2]oct-3-yl)-1H-benz[de] isoquinolin-1-one derivatives and intermediates useful therein | SYNTEX (U.S.A.) INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5510486-A | Process for preparing 2-(1-azabicyclo 2.2.2!oct-3-yl)-2,3,3A,4,5,6-hexahydro-1H-benz de!isoquinolin-1-one | SYNTEX (U.S.A.) INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5492914-A | ADMINISTERING TO TREAT A CONDITION CHOSEN FROM EMESIS, PSYCHOSIS, ANXIETY/DEPRESSIVE STATE, HYPERTENSION, ARRHYTHMIA AND PAIN | SYNTEX (U.S.A.) INC. (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1996001824-A1 | PROCESS FOR THE PREPARATION OF 2-(1-AZABICYCLO(2.2.2)OCT-3-YL) -2,4,5,6-TETRAHYDRO-1H-BENZ(DE)ISOQUINOLIN-1-ONE AND INTERMEDIATE PRODUCT | F. HOFFMANN-LA ROCHE AG (CH) | 1996-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226105-A1 | TIED-BACK BENZAMIDE DERIVATIVES AS POTENT ROCK INHIBITORS | MYLK, ROCK1, MYLK2 | CYP2C19 3978/4885SMN1; SMN2 558/4885SCN4A 2752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.