Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 3/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240221 | 0.87 | ERCC5 (0.63) | FEN1ERCC5GPR35ALDH1A1LMNA | |
| SCHEMBL13499113 | 0.87 | ERCC5 (0.61) | FEN1ERCC5GPR35ALDH1A1LMNA | |
| SCHEMBL6094162 | 0.82 | FEN1 (0.60) | FEN1ERCC5GPR35ALDH1A1LMNA | |
| SCHEMBL20438075 | 0.79 | NPC1 (0.50) | FEN1ERCC5ALDH1A1LMNAMEN1 | |
| SCHEMBL1739513 | 0.77 | ERCC5 (0.65) | FEN1ERCC5ALDH1A1LMNAMEN1 | |
| SCHEMBL1262256 | 0.76 | KLKB1 (0.47) | FEN1ERCC5ALDH1A1LMNAMEN1 | |
| SCHEMBL16563920 | 0.76 | MEN1 (0.52) | FEN1GPR35ALDH1A1LMNAMEN1 | |
| SCHEMBL1110081 | 0.75 | ERCC5 (0.63) | FEN1ERCC5ALDH1A1MEN1KMT2A | |
| SCHEMBL20913014 | 0.75 | CDC25B (0.57) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL30683710 | 0.75 | ERCC5 (0.63) | FEN1ERCC5ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743453-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | Pretzel Therapeutics, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025015178-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | disclosed |