SCHEMBL20913014

SCHEMBL20913014

CCOC(=O)C(=O)CC(=O)c1cccc2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.57
CDC25A P30304 1/20 0.53
CDC25C P30307 1/20 0.53
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 4/20 0.53
PTPN1 P18031 1/20 0.51
HPGD P15428 3/20 0.51
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
POLB P06746 3/20 0.49
GMNN O75496 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
MAPK1 P28482 2/20 0.49
BLM P54132 2/20 0.49
PMP22 Q01453 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
CMKLR1 Q99788 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
TSHR P16473 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11085302 0.93 CDC25B (0.53) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL854153 0.85 CDC25B (0.60) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL1739513 0.81 ERCC5 (0.65) ALDH1A1KDM4EMEN1KMT2APOLB
SCHEMBL697232 0.81 CDC25B (0.63) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL22062251 0.80 CDC25B (0.61) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL20438075 0.80 NPC1 (0.50) CDC25BALDH1A1KDM4EHPGDMEN1
SCHEMBL13499113 0.79 ERCC5 (0.61) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL1739431 0.79 ERCC5 (0.61) ALDH1A1KDM4EPTPN1MEN1KMT2A
SCHEMBL14921849 0.79 F2R (0.49) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL4910288 0.79 CDC25B (0.60) CDC25BCDC25ACDC25CALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119193-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Ivan Aleksandrovich Starikov 2019-04-25 US disclosed
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 EP disclosed
EP-3473098-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF Gorbunov, Sergei Valeryevich (RU) 2019-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119193-A1 COMPOSITION FOR REGULATING PLANT GROWTH, METHOD FOR TREATING PLANTS THEREWITH, AND ACTIVE INGREDIENT THEREOF OGDH, GOT1, OAT CDC25B 1086/4885CDC25A 882/4885CDC25C 1121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.