Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26690153 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP2A6PIK3CBCA2MAPT | |
| SCHEMBL19267571 | 0.85 | CYP1A2 (0.44) | CYP1A2CYP2A6PIK3CBCA2MAPT | |
| SCHEMBL7914260 | 0.78 | PIK3CB (0.65) | CYP1A2CYP2A6PIK3CBMAPTMAPK1 | |
| SCHEMBL29118016 | 0.75 | CYP1A2 (0.39) | CYP1A2CYP2A6PIK3CBCCR1CCR5 | |
| SCHEMBL12520036 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP2A6PIK3CBMAPTUHRF1 | |
| SCHEMBL22906826 | 0.70 | MAPT (0.44) | CYP1A2CYP2A6MAPTROCK1 | |
| SCHEMBL30670478 | 0.69 | PIK3CA (0.47) | PIK3CBMAPTCYP11B1CYP11B2 | |
| SCHEMBL17847214 | 0.69 | PIK3CA (0.47) | PIK3CBMAPTCYP11B1CYP11B2 | |
| SCHEMBL24110234 | 0.68 | HTR2C (0.57) | — | |
| SCHEMBL21547722 | 0.68 | MAPT (0.69) | CYP1A2CYP2A6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119212989-A | Pyrazole derivatives as STING agonists | 豪夫迈·罗氏有限公司 | 2024-12-27 | — | — | CN | disclosed |