Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318216 | 0.92 | MAP4K1 (0.70) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL31318213 | 0.91 | MAP4K1 (0.69) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL31318254 | 0.78 | MAP4K1 (0.70) | MAP4K1CYP3A4ABL1ITK | |
| SCHEMBL31318241 | 0.77 | MAP4K1 (0.81) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL13821698 | 0.73 | MAP3K7 (0.46) | ABL1BTKITK | |
| SCHEMBL31318231 | 0.73 | MAP4K1 (0.70) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL23101628 | 0.72 | MAP4K1 (1.00) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL31318226 | 0.72 | MAP4K1 (0.68) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL31318218 | 0.72 | MAP4K1 (0.68) | MAP4K1CYP3A4ABL1 | |
| SCHEMBL23101678 | 0.71 | MAP4K1 (1.00) | MAP4K1CYP3A4ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118894852-A | Polysubstituted indazole compound and preparation method and application thereof | 甫康（上海）健康科技有限责任公司 | 2024-11-05 | — | — | CN | disclosed |