Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318574 | 0.86 | NOTUM (0.54) | SHMT2NOTUMMAPTTHRBLMNA | |
| SCHEMBL31318540 | 0.78 | NOTUM (0.56) | SHMT2NOTUMMAPTTHRBLMNA | |
| SCHEMBL31058510 | 0.77 | PDE4A (0.75) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7022539 | 0.77 | AVPR1A (0.53) | SHMT2ALDH1A1NOTUMMAPTTHRB | |
| SCHEMBL31318527 | 0.77 | NOTUM (0.54) | SHMT2ALDH1A1NOTUMMAPTTHRB | |
| SCHEMBL31318509 | 0.77 | MAPT (0.56) | SHMT2NOTUMMAPTTHRBLMNA | |
| SCHEMBL31399227 | 0.76 | PDE4A (0.60) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL31399210 | 0.76 | PDE4A (0.60) | ALDH1A1MAPTPDE4APDE4BPDE4C | |
| SCHEMBL7020943 | 0.76 | AVPR1A (0.55) | SHMT2ALDH1A1NOTUMMAPTTHRB | |
| SCHEMBL7352710 | 0.74 | NOTUM (0.60) | SHMT2ALDH1A1NOTUMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |