Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318574 | 0.87 | NOTUM (0.54) | NOTUMSHMT2MAPTTHRBTP53 | |
| SCHEMBL31318527 | 0.87 | NOTUM (0.54) | NOTUMSHMT2MAPTTHRBTP53 | |
| SCHEMBL31318509 | 0.87 | MAPT (0.56) | NOTUMSHMT2MAPTTHRBTP53 | |
| SCHEMBL31318499 | 0.86 | TUBB4A (0.47) | NOTUMSHMT2MAPTTHRBTP53 | |
| SCHEMBL31318502 | 0.79 | TUBB4A (0.51) | NOTUMSHMT2MAPTTHRBTP53 | |
| SCHEMBL31318568 | 0.79 | LMNA (0.42) | THRBLMNATUBB4ATUBBTUBA3C | |
| SCHEMBL31318530 | 0.78 | SHMT2 (0.57) | NOTUMSHMT2MAPTTHRBTP53 | |
| SCHEMBL4900134 | 0.76 | NOTUM (0.56) | NOTUMMAPTTHRBTP53LMNA | |
| SCHEMBL10323593 | 0.74 | SLC22A12 (0.50) | NOTUMSHMT2MAPTTHRBLMNA | |
| SCHEMBL10324036 | 0.74 | SLC22A12 (0.47) | NOTUMSHMT2MAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |