SCHEMBL31318538

SCHEMBL31318538

Brc1ccc2c(c1)SCCN2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
ALDH1A1 P00352 1/20 0.55
GAA P10253 1/20 0.55
KMT2A Q03164 1/20 0.55
SNCA P37840 1/20 0.36
RYR2 Q92736 3/20 0.35
CTSL P07711 2/20 0.34
PARP10 Q53GL7 2/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PARP11 Q9NR21 1/20 0.33
PARP1 P09874 1/20 0.33
TGM2 P21980 1/20 0.32
CES1 P23141 1/20 0.32
PNMT P11086 1/20 0.32
ASIC3 Q9UHC3 1/20 0.32
BRD4 O60885 1/20 0.32
AHR P35869 2/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1816443 0.86 MEN1 (0.53) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL8472050 0.79 SNCA (0.38) MEN1ALDH1A1GAAKMT2ASNCA
SCHEMBL7238837 0.77 SNCA (0.34) MEN1ALDH1A1GAAKMT2ASNCA
SCHEMBL30657972 0.77 PARP10 (0.54) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL26653947 0.77 PARP10 (0.54) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL31318567 0.76 GAA (0.55) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL31552720 0.76 KMT2A (0.55) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL9032903 0.76 MEN1 (0.55) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL22232989 0.76 MEN1 (0.55) MEN1ALDH1A1GAAKMT2ARYR2
SCHEMBL19751453 0.76 GAA (0.55) MEN1ALDH1A1GAAKMT2ARYR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119059989-A URAT1 inhibitor, preparation method and application thereof 中国药科大学 2024-12-03 CN disclosed