Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19751453 | 1.00 | GAA (0.55) | GAAMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL10226479 | 0.86 | GAA (0.53) | GAAMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL18087623 | 0.85 | ALDH1A1 (0.49) | GAAMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL8469717 | 0.79 | EPHX2 (0.52) | GAAMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL31552720 | 0.76 | KMT2A (0.55) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22232989 | 0.76 | MEN1 (0.55) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31318538 | 0.76 | MEN1 (0.55) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9032903 | 0.76 | MEN1 (0.55) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5636666 | 0.76 | ALDH1A1 (0.42) | GAAMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL15828678 | 0.76 | ALDH1A1 (0.50) | GAAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |