SCHEMBL3131966

SCHEMBL3131966

O=C(N1CCOC1)N1CCOC1

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.58
TP53 P04637 1/20 0.58
KMT2A Q03164 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.48
MAPT P10636 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA9 Q16790 1/20 0.48
RECQL P46063 1/20 0.45
MMP1 P03956 1/20 0.44
MMP3 P08254 1/20 0.44
MMP8 P22894 1/20 0.44
AKR1C3 P42330 5/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2899860 0.82 MEN1 (0.80) MEN1TP53KMT2ASMN1; SMN2MAPT
SCHEMBL908027 0.81
SCHEMBL11741744 0.80 MEN1 (0.85) MEN1TP53KMT2ASMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL28000052 0.80 MEN1 (0.76) MEN1TP53KMT2ASMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL27660773 0.80 MEN1 (0.76) MEN1TP53KMT2ASMN1; SMN2MAPT
SCHEMBL6054511 0.79
SCHEMBL28044481 0.79
SCHEMBL5727806 0.79
SCHEMBL4124349 0.79
SCHEMBL30677423 0.76 MEN1 (0.95) MEN1TP53KMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105778049-A Isocyanate modified epoxide resin and application thereof 广东广山新材料有限公司 2016-07-20 CN claimed
CN-105601886-A Isocyanate modified epoxy resin and application GUANG SHAN NEW MAT CO LTD 2016-05-25 CN claimed
CN-105566613-A Isocyanate modified epoxy resin and application GUANGSHAN NEW MAT CO LTD 2016-05-11 CN claimed
CN-105524253-A Isocyanate modified epoxy resin and application thereof GUANG SHAN NEW MAT CO LTD 2016-04-27 CN claimed
CN-105482076-A Isocyanate modified epoxy resin and application GUANGSHAN NEW MAT CO LTD 2016-04-13 CN claimed
CN-105482075-A Isocyanate modified epoxy resin and application GUANGSHAN NEW MAT CO LTD 2016-04-13 CN claimed
CN-105778049-A Isocyanate modified epoxide resin and application thereof 广东广山新材料有限公司 2016-07-20 CN disclosed
CN-105601886-A Isocyanate modified epoxy resin and application GUANG SHAN NEW MAT CO LTD 2016-05-25 CN disclosed
CN-105566613-A Isocyanate modified epoxy resin and application GUANGSHAN NEW MAT CO LTD 2016-05-11 CN disclosed
CN-105524253-A Isocyanate modified epoxy resin and application thereof GUANG SHAN NEW MAT CO LTD 2016-04-27 CN disclosed
CN-105482076-A Isocyanate modified epoxy resin and application GUANGSHAN NEW MAT CO LTD 2016-04-13 CN disclosed
CN-105482075-A Isocyanate modified epoxy resin and application GUANGSHAN NEW MAT CO LTD 2016-04-13 CN disclosed
WO-2010018177-A1 REACTION PRODUCTS OF OXAZOLIDINE DERIVATIVES AND OF BISOXAZOLIDINE DERIVATIVES, IN PARTICULAR WITH DERIVATIVES OF HYDROXYAROMATICS AND OF NITROGEN-CONTAINING COMPOUNDS, SUCH AS AMINOTRIAZINES BOREALIS AGROLINZ MELAMINE GMBH (AT) 2010-02-18 WO disclosed