SCHEMBL908027

SCHEMBL908027

O=C(O)N1CCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29819156 0.85
SCHEMBL55421 0.83
SCHEMBL27840293 0.83 CA12 (0.56)
Hydrochloric Acid SCHEMBL2686905 0.81 CA12 (0.54)
SCHEMBL3131966 0.81 MEN1 (0.58)
SCHEMBL6054511 0.77
SCHEMBL4124349 0.77
SCHEMBL5727806 0.77
SCHEMBL28044481 0.77
Formic Acid SCHEMBL18578706 0.75 SMN1; SMN2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2499120-A1 NOVEL 1,3-OXAZOLIDINE COMPOUNDS AND THEIR USE AS RENIN INHIBITORS Novadex Pharmaceuticals AB (SE) 2012-09-19 EP claimed
CN-102603724-A Method for purifying and refining dimethoxy taxane compound JIANGSU HONGDOUSHAN BIOLOG TECHNOLOGY CO LTD 2012-07-25 CN claimed
CN-101128449-A Process of preparing docetaxel SERIPHARM (FR) 2008-02-20 CN claimed
EP-1453789-A2 N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES Elan Pharmaceuticals, Inc. (US) 2004-09-08 EP claimed
WO-2003040096-A2 N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES ELAN PHARMACEUTICALS, INC. (US) 2003-05-15 WO claimed
JP-2002522482-A 2002-07-23 JP claimed
EP-1104300-A2 CARBOXYLIC ACIDS AND ISOSTERES OF HETEROCYCLIC RING COMPOUNDS HAVING MULTIPLE HETEROATOMS FOR VISION AND MEMORY DISORDERS GPI NIL Holdings, Inc. (US) 2001-06-06 EP claimed
WO-2000009106-A2 CARBOXYLIC ACIDS AND ISOSTERES OF HETEROCYCLIC RING COMPOUNDS HAVING MULTIPLE HETEROATOMS FOR VISION AND MEMORY DISORDERS GPI NIL HOLDINGS, INC. (US) 2000-02-24 WO claimed
US-12312361-B2 Methods for practical synthesis of deuterated amino acids ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-05-27 US disclosed
WO-2025080946-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2025-04-17 WO disclosed
WO-2024259342-A2 METHODS FOR SYNTHESIZING ΑLPHA-DEUTERATED ΑLPHA-AMINO ACIDS AND DERIVATIVES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2024-12-19 WO disclosed
US-20240239771-A1 BACTERIAL EFFLUX PUMP INHIBITORS TAXIS PHARMACEUTICALS, INC. 2024-07-18 US disclosed
WO-2024061211-A1 LIPID COMPOUND FOR NUCLEIC ACID DELIVERY, AND RELATED USE AND MEDICAMENT COMPRISING SAME 中国医学科学院基础医学研究所 2024-03-28 WO disclosed
WO-2024034657-A1 PHARMACEUTICAL COMPOSITION COMPRISING HETEROCYCLIC COMPOUND アステラス製薬株式会社 2024-02-15 WO disclosed
CN-1210525-A Taxoids, their preparation and pharmaceutical compositions containing them RHONE POULENC RORER SA (FR) 1999-03-10 CN disclosed
CN-1175953-A Novel dipeptide amidines as thrombin inhibitors BASF AG (DE) 1998-03-11 CN disclosed
EP-0751145-A2 HIV-protease inhibitors Japan Energy Corporation (JP) 1997-01-02 EP disclosed
CN-1116823-A Therapeutic uses and delivery systems for dehydroepiandrosterone ENDORECHERCHE INC (CA) 1996-02-14 CN disclosed
US-5380945-A Vascular system disorders ABBOTT LABORATORIES (US) 1995-01-10 US disclosed
CN-1087905-A The method for preparing derivative of taxane RHONE POULENC RORER SA (FR) 1994-06-15 CN disclosed