Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131980 | 1.00 | SIRT2 (0.50) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL11510186 | 0.88 | PTGS2 (0.54) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL11404421 | 0.83 | MAOB (0.46) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL11413898 | 0.83 | MAOB (0.46) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL11413900 | 0.83 | MAOB (0.46) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL28490458 | 0.83 | MAOB (0.68) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL14337029 | 0.83 | MAOB (0.68) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL11404425 | 0.83 | MAOB (0.46) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL28156061 | 0.81 | MAOB (0.66) | SIRT2ALDH1A1L3MBTL1HPGDLMNA | |
| SCHEMBL18848385 | 0.81 | SIRT2 (0.46) | SIRT2ALDH1A1L3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035948-A1 | NOVEL (1,3-BUTADIEN-2-YL)METHYLAMINE DERIVATIVES AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2010-04-01 | — | — | WO | disclosed |