Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319703 | 0.76 | CCR1 (0.46) | CCR1CCR5CCR8SYKPOLB | |
| SCHEMBL31319561 | 0.72 | CCR1 (0.41) | CCR1CCR5CCR8CDK2DYRK1A | |
| SCHEMBL31319558 | 0.72 | CCR1 (0.41) | CCR1CCR5CCR8CDK2DYRK1A | |
| SCHEMBL31319716 | 0.71 | CCR1 (0.44) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL31438282 | 0.69 | AHR (0.47) | DYRK1AAHR | |
| SCHEMBL182529 | 0.69 | CCR1 (1.00) | CCR1CCR5CCR8SYKNOS3 | |
| SCHEMBL29395249 | 0.69 | CCR1 (1.00) | CCR1CCR5CCR8SYKNOS3 | |
| SCHEMBL7228502 | 0.68 | CCR1 (0.56) | CCR1CCR5CCR8PIK3CAPIK3CB | |
| SCHEMBL31319726 | 0.68 | AHR (0.39) | DYRK1AAHR | |
| SCHEMBL12885503 | 0.68 | CCR1 (0.56) | CCR1CCR5CCR8POLBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |