Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319703 | 0.75 | CCR1 (0.46) | CCR1CCR5CCR8AHRTNF | |
| SCHEMBL30752361 | 0.73 | AHR (0.39) | AHRTNFRIPK1DYRK1A | |
| SCHEMBL31319726 | 0.73 | AHR (0.39) | HDAC6AHRMETAP2TNFRIPK1 | |
| SCHEMBL31438282 | 0.71 | AHR (0.47) | AHRTNFRIPK1GRM5AXL | |
| SCHEMBL31319759 | 0.71 | CCR1 (0.49) | CCR1CCR5CCR8AHRNOS3 | |
| SCHEMBL31319712 | 0.70 | AHR (0.42) | AHRTNFRIPK1GRM5AXL | |
| SCHEMBL17659438 | 0.69 | AHR (0.52) | CCR8AHRTNFRIPK1AR | |
| SCHEMBL31438285 | 0.67 | AHR (0.50) | AHRTNFRIPK1CYP2A6AXL | |
| SCHEMBL31438254 | 0.67 | AHR (0.46) | AHRTNFRIPK1CYP3A4LMNA | |
| SCHEMBL31438268 | 0.67 | AHR (0.39) | AHRTNFRIPK1AXLPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |