Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426475 | 0.86 | HDAC1 (0.48) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL29577611 | 0.85 | JAK1 (0.45) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL21457806 | 0.85 | JAK1 (0.45) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL29577284 | 0.82 | DPP4 (0.42) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL21457826 | 0.82 | DPP4 (0.42) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL30427174 | 0.82 | HSD11B1 (0.44) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL31105124 | 0.82 | HSD11B1 (0.44) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL19212120 | 0.82 | HSD11B1 (0.43) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL19212044 | 0.81 | HSD11B1 (0.41) | HSD11B1JAK1CHRM2CHRM1CHRM3 | |
| SCHEMBL29707434 | 0.81 | HSD11B1 (0.41) | HSD11B1JAK1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219637-A | Aromatic heterobicyclic compounds and antiviral uses thereof | 苏州爱科百发生物医药技术有限公司 | 2024-12-31 | — | — | CN | disclosed |