Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 3/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31380068 | 0.91 | EPHX2 (0.37) | JAK3JAK2JAK1TYK2EPHX2 | |
| SCHEMBL31320087 | 0.81 | JAK3 (0.34) | JAK3JAK2JAK1TYK2EPHX2 | |
| SCHEMBL31380070 | 0.79 | EPHX2 (0.33) | EPHX2 | |
| SCHEMBL22712403 | 0.72 | THRB (0.50) | JAK3JAK2JAK1TYK2EPHX2 | |
| Hydrochloric Acid SCHEMBL31320052 | 0.69 | SMN1; SMN2 (0.33) | EPHX2 | |
| SCHEMBL24826722 | 0.67 | KDM4E (0.41) | JAK3JAK2JAK1TYK2EPHX2 | |
| SCHEMBL18788539 | 0.67 | THRB (0.45) | JAK3JAK2JAK1TYK2EPHX2 | |
| SCHEMBL27167765 | 0.67 | NAMPT (0.40) | JAK3JAK1KDM4EMAPTTHRB | |
| SCHEMBL31380056 | 0.66 | EPHX2 (0.39) | JAK3JAK2JAK1TYK2EPHX2 | |
| SCHEMBL31320106 | 0.66 | EPHX2 (0.39) | JAK3JAK2JAK1TYK2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025036713-A1 | PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-02-20 | — | — | WO | disclosed |