Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30887307 | 0.83 | ARG1 (0.47) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18892648 | 0.81 | ARG1 (0.46) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7766573 | 0.80 | GRIN2D (0.45) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11046478 | 0.80 | DRD3 (0.51) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18892593 | 0.79 | ARG1 (0.44) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9811629 | 0.79 | GRIN2D (0.44) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30938552 | 0.78 | DRD3 (0.58) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16611675 | 0.76 | GRIN2D (0.41) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16325359 | 0.76 | GRIN2D (0.41) | ARG1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14544406 | 0.76 | GRIN2D (0.41) | ARG1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |