Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 14/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118269 | 0.93 | PDE4B (0.41) | PDE4BGRM2NR3C2PDE4APDE4C | |
| SCHEMBL3132258 | 0.89 | PDE4B (0.42) | PDE4BGRM2NR3C2PRKDCPDE4A | |
| SCHEMBL3131862 | 0.87 | PDE4B (0.38) | PDE4BNR3C2PRKDCPDE4APDE4C | |
| SCHEMBL1157700 | 0.87 | PDE4B (0.44) | PDE4BGRM2NR3C2PDE4APDE4C | |
| SCHEMBL3118133 | 0.86 | NAPRT (0.45) | PDE4BGRM2NR3C2PDE4APDE4C | |
| SCHEMBL7950601 | 0.85 | PDE4B (0.44) | PDE4BGRM2NR3C2PRKDCPDE4A | |
| SCHEMBL1159028 | 0.84 | GRM2 (0.44) | PDE4BGRM2PDE4APDE4CPDE4D | |
| SCHEMBL3132285 | 0.83 | GRM2 (0.43) | PDE4BGRM2PDE4APDE4CPDE4D | |
| SCHEMBL3126626 | 0.83 | TAAR1 (0.44) | PDE4BGRM2PDE4APDE4CPDE4D | |
| SCHEMBL7945403 | 0.83 | PDE4B (0.43) | PDE4BGRM2NR3C2PDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |