SCHEMBL31323380

SCHEMBL31323380

CCN(CC)C(=O)Nc1nc(C)c(-c2ccc(OC)c(S(=O)(=O)Nc3ccc(O)cc3)c2)s1

nearest known ligand 0.75

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PIK3C2G O75747 5/20 0.75
PIK3CD O00329 5/20 0.75
PIK3CG P48736 4/20 0.75
PIK3CA P42336 2/20 0.75
PI4KB Q9UBF8 13/20 0.71
PIK3C3 Q8NEB9 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14851656 1.00 PIK3C2G (0.75) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851651 0.93 PIK3C2G (0.73) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL16490446 0.90 PIK3CG (0.63) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851849 0.89 PIK3C2G (0.79) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851607 0.87 PIK3C2G (0.82) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851641 0.86 PIK3C2G (0.80) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL29420845 0.86 PIK3CD (1.00) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851574 0.86 PIK3CD (1.00) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851648 0.86 PI4KB (0.81) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB
SCHEMBL14851581 0.85 PIK3C2G (0.79) PIK3C2GPIK3CDPIK3CGPIK3CAPI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3419980-B1 PI-KINASE INHIBITORS WITH ANTI-INFECTIVE ACTIVITY UNIV LELAND STANFORD JUNIOR (US) 2025-01-01 EP disclosed