SCHEMBL31324935

SCHEMBL31324935

OCc1ccc(Br)c(F)c1CO

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31324927 1.00 GPR17 (0.30) GPR17
SCHEMBL31614969 0.83
SCHEMBL855176 0.82 KDM1A (0.35)
SCHEMBL2064221 0.80 CYP1A2 (0.33) GPR17
SCHEMBL3310848 0.77 CES2 (0.38)
SCHEMBL30056204 0.77 DRD4 (0.36)
SCHEMBL25377353 0.77 KDM1A (0.32)
SCHEMBL1570876 0.77 KDM1A (0.32)
SCHEMBL2989130 0.77 TAAR1 (0.34)
SCHEMBL19792295 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504724-A Intermediates and methods of bicyclic compounds as CDK inhibitors 百济神州(北京)生物科技有限公司 2025-02-25 CN disclosed