SCHEMBL31325652

SCHEMBL31325652

c1ccc2[nH]c(Nc3c[nH]c4ccccc34)nc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.59
RAB9A P51151 8/20 0.56
SMN1; SMN2 Q16637 8/20 0.56
MAPT P10636 6/20 0.56
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
NPC1 O15118 5/20 0.56
LMNA P02545 4/20 0.56
TDP1 Q9NUW8 2/20 0.56
MPO P05164 1/20 0.56
HTT P42858 1/20 0.56
GFER P55789 1/20 0.56
MAP4K4 O95819 1/20 0.56
FLT3 P36888 1/20 0.56
SYK P43405 1/20 0.56
MAP4K2 Q12851 1/20 0.56
AURKB Q96GD4 1/20 0.56
CLK4 Q9HAZ1 1/20 0.56
IRAK4 Q9NWZ3 1/20 0.56
MAP3K20 Q9NYL2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22717647 1.00 GAA (0.59) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL30166990 0.85 GAA (0.50) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24996192 0.85 GAA (0.50) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL28967627 0.85 GAA (0.50) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24997090 0.85 RAB9A (0.50) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24996874 0.85 GAA (0.50) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24996835 0.85 GAA (0.50) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24996873 0.85 MEN1 (0.57) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24996844 0.84 GAA (0.49) GAARAB9ASMN1; SMN2MAPTMEN1
SCHEMBL24996187 0.82 GAA (0.50) GAARAB9ASMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115768761-B Novel benzimidazole derivatives 卡尔那生物科学株式会社 2025-02-25 CN claimed