Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775044 | 0.90 | THRB (0.45) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL27863692 | 0.90 | THRB (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL27849592 | 0.88 | THRB (0.43) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2345676 | 0.87 | TSHR (0.44) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL7527455 | 0.86 | TSHR (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL21066753 | 0.85 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL21066797 | 0.85 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL4859732 | 0.84 | TSHR (0.47) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9402704 | 0.82 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL7532392 | 0.82 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053629-A1 | ASYMMETRIC PHOTO-PATTERNABLE SOL-GEL PRECURSORS AND THEIR METHODS OF PREPARATION | NITTO DENKO CORPORATION (JP) | 2010-05-14 | — | — | WO | disclosed |