SCHEMBL31325762

SCHEMBL31325762

COc1ccc(C(=O)O)cc1C(C)(C)C

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARA P10276 2/20 0.73
RARB P10826 2/20 0.73
RARG P13631 2/20 0.73
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
CA7 P43166 1/20 0.65
TPMT P51580 1/20 0.65
CA9 Q16790 1/20 0.65
CA14 Q9ULX7 1/20 0.65
WDR5 P61964 1/20 0.60
HTT P42858 2/20 0.59
LMNA P02545 2/20 0.59
RAB9A P51151 2/20 0.59
MAPK1 P28482 1/20 0.59
PKM P14618 1/20 0.57
TSHR P16473 4/20 0.56
TTR P02766 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421835 1.00 RARA (0.73) RARARARBRARGCA12CA1
Hydrochloric Acid SCHEMBL9131236 0.98 RARA (0.71) RARARARBRARGCA12CA1
SCHEMBL2773345 0.86 RARA (0.61) RARARARBRARGCA12CA1
SCHEMBL1542321 0.86 NR1H4 (0.66) RARARARBRARGCA12CA1
SCHEMBL980501 0.85 RARB (1.00) RARARARBRARGCA12CA1
SCHEMBL30301169 0.85 RARB (1.00) RARARARBRARGCA12CA1
SCHEMBL9132737 0.85 RARA (0.56) RARARARBRARGCA12CA1
SCHEMBL615379 0.84 CA12 (0.62) RARARARBRARGCA12CA1
SCHEMBL5218149 0.84 RARA (0.56) RARARARBRARGCA12CA1
SCHEMBL22601523 0.84 RARA (0.56) RARARARBRARGCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743457-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR THERAPEUTIC USE 4M THERAPEUTICS INC. (US) 2026-05-20 EP disclosed
WO-2025015045-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 FOR THERAPEUTIC USE 4M THERAPEUTICS INC. (US) 2025-01-16 WO disclosed