Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21978548 | 1.00 | ATM (0.37) | ATMERN1SLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL21994892 | 0.92 | DGAT1 (0.34) | ATMERN1PPARGGAAGFER | |
| SCHEMBL21994667 | 0.88 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3USP2TP53 | |
| SCHEMBL22035325 | 0.88 | ERN1 (0.36) | ATMERN1PPARGUSP2TP53 | |
| SCHEMBL30660153 | 0.88 | ERN1 (0.36) | ATMERN1PPARGUSP2TP53 | |
| SCHEMBL21994796 | 0.82 | MAPT (0.36) | SLC6A2SLC6A4SLC6A3PPARGUSP2 | |
| SCHEMBL21978708 | 0.81 | PCSK9 (0.40) | ATMSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21978392 | 0.79 | GAA (0.38) | PPARGTP53MAPK1KDM4EALDH1A1 | |
| SCHEMBL21978877 | 0.79 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3PPARG | |
| SCHEMBL22035323 | 0.78 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |