Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31327064

NC1CC(N2CCN(C3CC3)CC2)C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 5/20 0.35
HRH3 Q9Y5N1 3/20 0.35
ALOX15 P16050 1/20 0.34
DPP7 Q9UHL4 6/20 0.34
DPP4 P27487 5/20 0.34
DPP8 Q6V1X1 3/20 0.34
SIGMAR1 Q99720 1/20 0.33
KCNH2 Q12809 1/20 0.32
DPP9 Q86TI2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31327095 0.89 KDM4E (0.37) KDM4EALDH1A1HRH3ALOX15DPP7
Trifluoroacetic Acid SCHEMBL31327078 0.83 CYP1A2 (0.36) DPP7DPP4DPP8SIGMAR1
Trifluoroacetic Acid SCHEMBL31327108 0.83 PRCP (0.35) KDM4EALDH1A1DPP4DPP8KCNH2
Trifluoroacetic Acid SCHEMBL31327141 0.81 HRH3 (0.40) HRH3DPP7DPP4DPP8SIGMAR1
Trifluoroacetic Acid SCHEMBL1700238 0.80 HRH3 (0.43) HRH3
SCHEMBL31327023 0.80 PHGDH (0.30) HRH3
Trifluoroacetic Acid SCHEMBL31327037 0.79 IRAK4 (0.36) KDM4EALDH1A1HRH3ALOX15DPP7
Trifluoroacetic Acid SCHEMBL18225933 0.79 KDM1A (0.40) ALDH1A1HRH3DPP7DPP4DPP8
Trifluoroacetic Acid SCHEMBL21645222 0.78 L3MBTL1 (0.39) KDM4EALDH1A1HRH3DPP4DPP8
Trifluoroacetic Acid SCHEMBL1700180 0.78 L3MBTL1 (0.39) KDM4EALDH1A1HRH3DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066383-A1 PDE 7 MODULATOR COMPOUNDS OMEROS CORPORATION 2025-02-27 US disclosed
WO-2025042956-A1 PDE 7 MODULATOR COMPOUNDS OMEROS CORPORATION (US) 2025-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066383-A1 PDE 7 MODULATOR COMPOUNDS PDE7A, PDE3A, PDE3B KDM4E 915/4885ALDH1A1 1479/4885HRH3 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.