Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464260 | 1.00 | MAPT (0.64) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL31328322 | 0.83 | SIRT1 (0.61) | MAPTKMT2AMEN1LMNAKDM4E | |
| SCHEMBL31328297 | 0.83 | SIRT1 (0.61) | MAPTKMT2AMEN1LMNAKDM4E | |
| SCHEMBL31328324 | 0.83 | SIRT1 (0.61) | MAPTKMT2AMEN1LMNAKDM4E | |
| SCHEMBL31328303 | 0.79 | MAPT (0.68) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL31328304 | 0.79 | MAPT (0.68) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL4725046 | 0.78 | MEN1 (1.00) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL31612407 | 0.78 | MEN1 (1.00) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL31328310 | 0.77 | MAPT (0.66) | MAPTKMT2AMEN1LMNANPSR1 | |
| SCHEMBL31328301 | 0.77 | MAPT (0.66) | MAPTKMT2AMEN1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007928-A1 | INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州湃芮生物科技有限公司 | 2025-01-09 | — | — | WO | disclosed |