Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.30 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31328669 | 0.91 | CAMKK1 (0.32) | GRM5 | |
| SCHEMBL31380685 | 0.90 | GRM5 (0.33) | GRM5 | |
| SCHEMBL23043188 | 0.85 | GRM5 (0.30) | GRM5 | |
| SCHEMBL31328721 | 0.85 | — | — | |
| SCHEMBL29418866 | 0.85 | GRM5 (0.30) | GRM5 | |
| SCHEMBL31732832 | 0.85 | KDM4E (0.33) | — | |
| SCHEMBL31328518 | 0.84 | — | — | |
| SCHEMBL30707569 | 0.83 | — | — | |
| SCHEMBL27302945 | 0.83 | GRM5 (0.32) | GRM5 | |
| SCHEMBL31732909 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040767-A1 | 2-(3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL)-1,3,5-TRIAZINE DERIVATIVES AS KRAS G12D INHIBITORS FOR THE TREATMENT OF CANCER | SANOFI (FR) | 2025-02-27 | — | — | WO | disclosed |