SCHEMBL31380685

SCHEMBL31380685

COCOc1cc(C(=O)OC)c2c(C#C[Si](C(C)C)(C(C)C)C(C)C)c(F)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.33
MET P08581 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31328669 0.91 CAMKK1 (0.32) GRM5S1PR3
SCHEMBL31328629 0.90 GRM5 (0.32) GRM5
SCHEMBL31732832 0.88 KDM4E (0.33)
SCHEMBL23043188 0.85 GRM5 (0.30) GRM5
SCHEMBL29418866 0.85 GRM5 (0.30) GRM5
SCHEMBL31328518 0.84
SCHEMBL30707569 0.83
SCHEMBL27302945 0.83 GRM5 (0.32) GRM5
SCHEMBL29876829 0.83
SCHEMBL31732909 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025236100-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2025-11-20 WO disclosed
WO-2025026903-A1 IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2025-02-06 WO disclosed