Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 19/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31328546 | 1.00 | KRAS (0.40) | KRASGPR119 | |
| SCHEMBL31328675 | 1.00 | KRAS (0.40) | KRASGPR119 | |
| SCHEMBL29151485 | 1.00 | KRAS (0.40) | KRASGPR119 | |
| SCHEMBL31328620 | 0.90 | KRAS (0.40) | KRASGPR119 | |
| SCHEMBL31328703 | 0.90 | KRAS (0.39) | KRASGPR119 | |
| SCHEMBL31328506 | 0.90 | KRAS (0.39) | KRASGPR119 | |
| SCHEMBL31328569 | 0.90 | KRAS (0.39) | KRASGPR119 | |
| SCHEMBL31328727 | 0.88 | GPR119 (0.40) | KRASGPR119 | |
| SCHEMBL31328535 | 0.88 | KRAS (0.39) | KRASGPR119 | |
| SCHEMBL31328623 | 0.88 | KRAS (0.39) | KRASGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025040767-A1 | 2-(3,8-DIAZABICYCLO[3.2.1]OCTAN-3-YL)-1,3,5-TRIAZINE DERIVATIVES AS KRAS G12D INHIBITORS FOR THE TREATMENT OF CANCER | SANOFI (FR) | 2025-02-27 | — | — | WO | disclosed |