Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CKS1B | P61024 | 2/20 | 0.50 |
| ▸ | SKP1 | P63208 | 2/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329004 | 1.00 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6363304 | 0.85 | MEN1 (0.65) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22411451 | 0.85 | MAPT (0.61) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29361285 | 0.84 | MAPT (0.57) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29426702 | 0.84 | MAPT (0.56) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4137116 | 0.84 | MAPT (0.56) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1393764 | 0.84 | MAPT (0.56) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30150192 | 0.84 | MAPT (0.56) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL594965 | 0.84 | MAPT (0.56) | GPR119MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22388849 | 0.84 | GPR119 (0.62) | GPR119MAPTALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007863-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-01-09 | — | — | WO | disclosed |