Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6094601 | 1.00 | MAPT (0.65) | MAPTGAAPTGS1SRD5A2CA1 | |
| SCHEMBL8374908 | 0.85 | MAPT (0.87) | MAPTGAACA1CA2CA9 | |
| SCHEMBL1173269 | 0.85 | P2RX1 (0.61) | MAPTGAAPTGS1CA1CA2 | |
| SCHEMBL28765131 | 0.82 | PTGS1 (0.57) | PTGS1SRD5A2CES2CES1HTT | |
| SCHEMBL5347968 | 0.82 | PTGS1 (0.59) | MAPTGAAPTGS1SRD5A2P2RX1 | |
| SCHEMBL3486347 | 0.81 | MAPT (0.61) | MAPTGAAPTGS1SRD5A2P2RX1 | |
| SCHEMBL3542735 | 0.81 | MAPT (0.67) | MAPTPTGS1SRD5A2CES2CES1 | |
| SCHEMBL10396396 | 0.81 | RECQL (0.53) | MAPTPTGS1SRD5A2P2RX1CES2 | |
| SCHEMBL8362275 | 0.81 | SRD5A2 (0.55) | GAAPTGS1SRD5A2CES2CES1 | |
| SCHEMBL38533242 | 0.81 | AKR1C3 (0.66) | SRD5A2CA1CA2CA9CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4461783-A1 | ELECTROCHROMIC COMPOUNDS, COMPOSITIONS AND OPTICAL ARTICLES CONTAINING THEM | Essilor International (FR) | 2024-11-13 | — | — | EP | disclosed |