Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.65 |
| ▸ | CDC25B | P30305 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751786 | 1.00 | AKR1C3 (0.66) | AKR1C3SRD5A2CDC25BATMNR4A1 | |
| SCHEMBL27524893 | 0.84 | AKR1C3 (0.91) | AKR1C3SRD5A2CDC25BATMNR4A1 | |
| SCHEMBL5310287 | 0.84 | AKR1C3 (0.58) | AKR1C3SRD5A2CDC25BATMNR4A1 | |
| SCHEMBL9537242 | 0.83 | KDM4E (0.62) | AKR1C3SRD5A2CDC25BCYP2C8CDC25A | |
| SCHEMBL1781341 | 0.83 | SRD5A2 (0.77) | SRD5A2CYP2C8CES2CES1ALDH1A1 | |
| SCHEMBL29550462 | 0.82 | TDP1 (0.66) | AKR1C3SRD5A2CDC25BATMNR4A1 | |
| SCHEMBL11176158 | 0.82 | TDP1 (0.66) | AKR1C3SRD5A2CDC25BATMNR4A1 | |
| SCHEMBL8362275 | 0.82 | SRD5A2 (0.55) | SRD5A2CYP2C8CES2CES1ALDH1A1 | |
| SCHEMBL9229493 | 0.81 | SRD5A2 (0.67) | AKR1C3SRD5A2CDC25BCDC25AHSD17B10 | |
| SCHEMBL6094601 | 0.81 | MAPT (0.65) | SRD5A2CYP2C8HSD17B10CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059950-A | Compounds with proteasome agonistic activity, preparation method and application thereof | 浙大城市学院 | 2026-05-19 | — | — | CN | disclosed |