SCHEMBL31329503

SCHEMBL31329503

Cc1ccc(-c2nnc(N[C@@H]3CCCN(C)C3)cc2C(F)(F)F)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IL1B P01584 14/20 1.00
NLRP3 Q96P20 11/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22654930 1.00 IL1B (1.00) IL1BNLRP3
SCHEMBL31329531 1.00 IL1B (1.00) IL1BNLRP3
SCHEMBL22654843 1.00 IL1B (1.00) IL1BNLRP3
SCHEMBL31329534 1.00 IL1B (1.00) IL1BNLRP3
SCHEMBL22654845 1.00 IL1B (1.00) IL1BNLRP3
SCHEMBL22654871 0.90 IL1B (1.00) IL1BNLRP3
SCHEMBL22654870 0.90 IL1B (1.00) IL1BNLRP3
SCHEMBL22655033 0.90 IL1B (1.00) IL1BNLRP3
SCHEMBL22654979 0.89 IL1B (1.00) IL1BNLRP3
SCHEMBL22654920 0.89 IL1B (1.00) IL1BNLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119732956-A NLRP3 inflammatory corpuscle inhibitor 诺华股份有限公司 2025-04-01 CN claimed
CN-113784957-B NLRP3 inflammatory corpuscle inhibitor 诺华股份有限公司 2025-02-28 CN claimed
CN-119732956-A NLRP3 inflammatory corpuscle inhibitor 诺华股份有限公司 2025-04-01 CN disclosed
CN-113784957-B NLRP3 inflammatory corpuscle inhibitor 诺华股份有限公司 2025-02-28 CN disclosed