Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 19/20 | 0.81 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22655145 | 1.00 | IL1B (0.81) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL22655047 | 1.00 | IL1B (0.81) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL22655050 | 1.00 | IL1B (0.81) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL31329547 | 1.00 | IL1B (0.81) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL31329518 | 1.00 | IL1B (0.81) | IL1BNLRP3KCNH2TNF | |
| Trifluoroacetic Acid SCHEMBL22655994 | 0.93 | IL1B (0.73) | IL1BNLRP3KCNH2TNF | |
| Trifluoroacetic Acid SCHEMBL22655996 | 0.93 | IL1B (0.73) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL22655060 | 0.90 | IL1B (1.00) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL22654928 | 0.90 | IL1B (1.00) | IL1BNLRP3KCNH2TNF | |
| SCHEMBL22654931 | 0.90 | IL1B (1.00) | IL1BNLRP3KCNH2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119732956-A | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-113784957-B | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119732956-A | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-113784957-B | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-02-28 | — | — | CN | disclosed |