Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529472 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA | |
| SCHEMBL5525935 | 0.87 | ALDH1A1 (0.72) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA | |
| SCHEMBL15154629 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL2382446 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL5530559 | 0.85 | ALDH1A1 (0.76) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA | |
| SCHEMBL15966805 | 0.85 | ALDH1A1 (0.77) | ALDH1A1KDM4ESMN1; SMN2LMNANPC1 | |
| SCHEMBL11383580 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA | |
| SCHEMBL5330384 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA | |
| SCHEMBL9273846 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA | |
| SCHEMBL14607235 | 0.83 | ALDH1A1 (0.66) | ALDH1A1KDM4ESMN1; SMN2ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115103841-B | Substituted quinolinone piperazine compounds useful as T cell activators | 百时美施贵宝公司 | 2024-12-27 | — | — | CN | disclosed |