Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906713 | 0.79 | KDM4E (0.40) | CHRNB2CHRNA4KDM4E | |
| SCHEMBL7098381 | 0.78 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1HTTGAA | |
| SCHEMBL7098852 | 0.78 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1HTTGAA | |
| SCHEMBL7103930 | 0.77 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1HTTGAA | |
| SCHEMBL7098393 | 0.77 | ALDH1A1 (0.40) | CHRNB2CHRNA4ALDH1A1HTTGAA | |
| SCHEMBL21367908 | 0.76 | KDM4E (0.38) | KDM4E | |
| SCHEMBL2250114 | 0.76 | HTT (0.52) | HTTKDM4E | |
| SCHEMBL7105555 | 0.75 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1HTTGAA | |
| SCHEMBL7101906 | 0.75 | ALDH1A1 (0.39) | CHRNB2CHRNA4ALDH1A1HTTGAA | |
| SCHEMBL25928002 | 0.74 | KDM4E (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249817-A1 | TRICYCLIC PKMYT1 KINASE INHIBITORS | ENLIVEN INC. (US) | 2024-12-05 | — | — | WO | disclosed |