Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | PDE8A | O60658 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PDE9A | O76083 | 1/20 | 0.47 |
| ▸ | PDE8B | O95263 | 1/20 | 0.47 |
| ▸ | PDE6A | P16499 | 1/20 | 0.47 |
| ▸ | PDE6G | P18545 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31330064 | 0.74 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL31386841 | 0.73 | GRIA1 (0.33) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL707973 | 0.71 | PDE2A (0.55) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL31330090 | 0.71 | PARP1 (0.43) | PARP1 | |
| SCHEMBL14431586 | 0.71 | PDE2A (0.58) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7269656 | 0.64 | PDE2A (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7506851 | 0.64 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL3493681 | 0.64 | GRIA1 (0.68) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL30989497 | 0.63 | PDE2A (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL30989496 | 0.63 | PDE2A (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371425-A | Nitrogen-containing heterocyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-01-28 | — | — | CN | disclosed |