Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP1 | P63208 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29736597 | 1.00 | SSTR4 (0.44) | SSTR4SYKSUV39H2MT-CO2MTNR1A | |
| SCHEMBL23089663 | 0.93 | SSTR4 (0.41) | SSTR4SYKSUV39H2BACE1ATR | |
| SCHEMBL22980358 | 0.82 | SSTR4 (0.37) | SSTR4SYKMTNR1AMTNR1BPAX8 | |
| SCHEMBL23107372 | 0.81 | SSTR4 (0.36) | SSTR4SYK | |
| SCHEMBL20580580 | 0.81 | SSTR4 (0.38) | SSTR4SYKPAX8 | |
| SCHEMBL24103634 | 0.80 | SSTR4 (0.43) | SSTR4SYKBACE1PAX8PDPK1 | |
| SCHEMBL30420159 | 0.80 | SSTR4 (0.43) | SSTR4SYKBACE1PAX8PDPK1 | |
| SCHEMBL23089228 | 0.80 | SYK (0.37) | SSTR4SYKATRNPSR1 | |
| SCHEMBL29424938 | 0.80 | SYK (0.37) | SSTR4SYKATRNPSR1 | |
| SCHEMBL23107325 | 0.79 | SSTR4 (0.37) | SSTR4SYKBACE1NPSR1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874700-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-114945366-B | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2025-01-07 | — | — | CN | disclosed |