Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3132643 | 0.98 | ALDH1A1 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL19746923 | 0.68 | ALDH1A1 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL20934793 | 0.68 | ALDH1A1 (0.40) | ALDH1A1KMT2A | |
| SCHEMBL19747940 | 0.68 | ALDH1A1 (0.35) | ALDH1A1KMT2A | |
| SCHEMBL20088503 | 0.66 | ALDH1A1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL20094289 | 0.62 | FUBP1 (0.37) | ALDH1A1 | |
| SCHEMBL31417186 | 0.61 | TP53 (0.35) | ALDH1A1KMT2A | |
| SCHEMBL20512222 | 0.61 | ALDH1A1 (0.55) | ALDH1A1KMT2A | |
| SCHEMBL17687767 | 0.61 | AHR (0.59) | KMT2A | |
| SCHEMBL3124587 | 0.60 | MALT1 (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784188-B1 | FUSED TRIAZOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK SHARP & DOHME (US) | 2010-07-14 | — | — | EP | disclosed |
| US-7625888-B2 | Fused triazole derivatives as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes | MERCK & CO., INC. (US) | 2009-12-01 | — | — | US | disclosed |
| US-20070208010-A1 | Fused Triazole Derivatives as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes | MERCK SHARP & DOHME CORP. | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208010-A1 | Fused Triazole Derivatives as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes | DPP4, DPP3, DPP7 | ALDH1A1 1223/4885KMT2A 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.