Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.32 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31330590 | 0.92 | P2RX7 (0.35) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL30722544 | 0.90 | GSK3B (0.37) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL26988724 | 0.90 | GSK3B (0.37) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL26988882 | 0.90 | GSK3B (0.37) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL30722668 | 0.90 | GSK3B (0.37) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL26988284 | 0.90 | GSK3B (0.37) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL24001694 | 0.89 | GSK3B (0.34) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL24002211 | 0.89 | GSK3B (0.34) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL24002208 | 0.89 | GSK3B (0.34) | GSK3BCYP1A2CYP2D6P2RX7PDE2A | |
| SCHEMBL30293379 | 0.89 | GSK3B (0.34) | GSK3BCYP1A2CYP2D6P2RX7PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720061-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-08 | — | — | EP | claimed |
| WO-2024246018-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-05 | — | — | WO | claimed |
| EP-4720061-A1 | TREM2 AGONISTS | F. Hoffmann-La Roche AG (CH) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246018-A1 | TREM2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-05 | — | — | WO | disclosed |