SCHEMBL31330664

SCHEMBL31330664

CC1CCN(c2ccc(C(=O)OC(C)(C)C)nn2)CC1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
HSP90AA1 P07900 1/20 0.43
PAX8 Q06710 1/20 0.43
KLF5 Q13887 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SCD O00767 1/20 0.42
DCTPP1 Q9H773 1/20 0.41
MAPT P10636 1/20 0.41
GPR119 Q8TDV5 2/20 0.41
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29058449 0.86 MEN1 (0.40) MEN1KMT2ASMN1; SMN2SCDDCTPP1
SCHEMBL30488972 0.86 SCD (0.44) MEN1KMT2ASMN1; SMN2SCDDCTPP1
SCHEMBL20075853 0.86 SCD (0.44) MEN1KMT2ASMN1; SMN2SCDDCTPP1
SCHEMBL30488995 0.86 MEN1 (0.40) MEN1KMT2ASMN1; SMN2SCDDCTPP1
SCHEMBL20046195 0.85 SCD (0.48) SCDDCTPP1
SCHEMBL20046190 0.83 SCD (0.42) MEN1KMT2ASMN1; SMN2SCDDCTPP1
SCHEMBL24629084 0.83 BPTF (0.47) MEN1KMT2ASCDDCTPP1GPR119
SCHEMBL31605540 0.82 GPR119 (0.53) MEN1KMT2ASMN1; SMN2SCDMAPT
SCHEMBL20046288 0.79 SCD (0.42) SCDDCTPP1GPR119LMNA
SCHEMBL20046463 0.75 HRH3 (0.52) SCDGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025011623-A1 CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海壹迪生物技术有限公司 2025-01-16 WO disclosed